{"id":10097,"date":"2026-06-05T15:13:07","date_gmt":"2026-06-05T21:13:07","guid":{"rendered":"https:\/\/aguilasalporvenir.com\/?p=10097"},"modified":"2026-06-05T15:13:07","modified_gmt":"2026-06-05T21:13:07","slug":"inmegen-impulsa-analisis-genomico-para-combatir-resistencia-de-bacterias-a-antibioticos","status":"publish","type":"post","link":"https:\/\/aguilasalporvenir.com\/index.php\/2026\/06\/05\/inmegen-impulsa-analisis-genomico-para-combatir-resistencia-de-bacterias-a-antibioticos\/","title":{"rendered":"Inmegen impulsa an\u00e1lisis gen\u00f3mico para combatir resistencia de bacterias a antibi\u00f3ticos"},"content":{"rendered":"<ul>\n<li><strong>Automedicaci\u00f3n y uso indiscriminado de antibi\u00f3ticos favorecen la resistencia antimicrobiana y reducen las opciones de tratamiento, se\u00f1ala especialista.<\/strong><\/li>\n<\/ul>\n<p>El Instituto Nacional de Medicina Gen\u00f3mica (Inmegen) desarrolla proyectos de vigilancia enfocados en identificar los mecanismos moleculares asociados a la resistencia bacteriana y fortalecer las estrategias de respuesta cl\u00ednica y epidemiol\u00f3gica.<\/p>\n<p>La subdirectora de Bioinform\u00e1tica del Inmegen, Laura Lucila G\u00f3mez Romero, explic\u00f3 que la resistencia antimicrobiana (RAM) ocurre cuando bacterias pat\u00f3genas desarrollan mecanismos gen\u00e9ticos que les permiten resistir a los antibi\u00f3ticos, ya sea mediante mutaciones en su material gen\u00e9tico o por intercambio natural de ADN entre bacterias, proceso mediante el cual pueden comparten genes de resistencia.<\/p>\n<p>En este contexto, uno de los principales esfuerzos es el proyecto \u201cFortalecimiento de la Vigilancia Gen\u00f3mica de\u00a0Acinetobacter baumannii\u00a0en Latinoam\u00e9rica\u201d, financiado por el Fondo Conjunto de Cooperaci\u00f3n M\u00e9xico-Chile y realizado en colaboraci\u00f3n con el Hospital Ju\u00e1rez de M\u00e9xico (HJM) y la Universidad de Santiago de Chile.<\/p>\n<p>El proyecto est\u00e1 dirigido por un equipo multinacional en el que participan la subdirectora de Bioinform\u00e1tica, Laura Lucila G\u00f3mez y Alberto Cedro, ambos investigadores del Inmegen y doctores en Ciencias Biom\u00e9dicas.<\/p>\n<p>Como parte de esta iniciativa se secuenciaron m\u00e1s \u00a0de 100 aislados bacterianos en M\u00e9xico y Chile, correspondientes a bacterias multirresistentes, con el objetivo de identificar los determinantes gen\u00e9ticos relacionados con la RAM y detectar posibles brotes hospitalarios.<\/p>\n<p>La especialista detall\u00f3 que el trabajo del Instituto Nacional de Medicina Gen\u00f3mica tambi\u00e9n incluye investigaciones sobre otros pat\u00f3genos prioritarios como\u00a0Klebsiella pneumoniae, Staphylococcus aureus\u00a0y\u00a0Mycobacterium\u00a0tuberculosis\u00a0resistentes a antibi\u00f3ticos.<\/p>\n<p>G\u00f3mez Romero advirti\u00f3 que la resistencia antimicrobiana representa uno de los principales desaf\u00edos para la salud p\u00fablica debido a que las bacterias dejan de responder a los tratamientos disponibles, lo que complica la atenci\u00f3n m\u00e9dica, incrementa las estancias hospitalarias y eleva el riesgo de mortalidad.<\/p>\n<p>\u201cCuando el pat\u00f3geno ya no reduce su tasa de crecimiento ni muere a causa del antibi\u00f3tico, se dice que es resistente\u201d, se\u00f1al\u00f3 la investigadora, quien destac\u00f3 que esta situaci\u00f3n dificulta el tratamiento de infecciones y puede derivar en cuadros m\u00e1s graves o sist\u00e9micos.<\/p>\n<p>Respecto al uso incorrecto de antibi\u00f3ticos, la especialista alert\u00f3 sobre los riesgos de la automedicaci\u00f3n y del consumo innecesario de antibi\u00f3ticos de amplio espectro, particularmente en infecciones virales donde estos medicamentos no tienen efecto.<\/p>\n<p>A\u00f1adi\u00f3 que el uso indiscriminado de antibi\u00f3ticos favorece la supervivencia de bacterias resistentes y la propagaci\u00f3n de genes de resistencia a otros microorganismos, por lo que recomend\u00f3 utilizar estos medicamentos \u00fanicamente bajo prescripci\u00f3n m\u00e9dica y, cuando sea posible, optar por tratamientos dirigidos espec\u00edficamente al pat\u00f3geno causante de la infecci\u00f3n.<\/p>\n<p>Finalmente, advirti\u00f3 que la resistencia antimicrobiana no solo incrementa los costos hospitalarios y prolonga la recuperaci\u00f3n de los pacientes, sino que tambi\u00e9n limita las opciones terap\u00e9uticas disponibles y obliga al uso de antibi\u00f3ticos de \u00faltima generaci\u00f3n, que suelen ser m\u00e1s costosos.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Automedicaci\u00f3n y uso indiscriminado de antibi\u00f3ticos favorecen la resistencia antimicrobiana y reducen las opciones de tratamiento, se\u00f1ala especialista. El Instituto [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10098,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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href=\"https:\/\/aguilasalporvenir.com\/index.php\/category\/blog\/\" rel=\"category tag\">Blog<\/a>","rttpg_excerpt":"Automedicaci\u00f3n y uso indiscriminado de antibi\u00f3ticos favorecen la resistencia antimicrobiana y reducen las opciones de tratamiento, se\u00f1ala especialista. El Instituto [&hellip;]","_links":{"self":[{"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/posts\/10097","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/comments?post=10097"}],"version-history":[{"count":1,"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/posts\/10097\/revisions"}],"predecessor-version":[{"id":10099,"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/posts\/10097\/revisions\/10099"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/media\/10098"}],"wp:attachment":[{"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/media?parent=10097"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/categories?post=10097"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/aguilasalporvenir.com\/index.php\/wp-json\/wp\/v2\/tags?post=10097"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}